Kitajiri S., Fukumoto K., Hata M., Sasaki H., Katsuno T., Nakagawa T., Ito J., Tsukita Sh., andTsukita Sa.* 2004.
Radixin deficiency causes deafness associated with progressive degeneration of
cochlear stereocilia.
J. Cell Biol. 166:559-570. [PUBMED]
Hoeflich K.P., Tsukita Sa., Hicks L., Kay C.M., Tsukita Sh., and Ikura M.* 2003.
Insights into a single rod-like helix in activated radixin required for
membrane-cytoskeletal cross-linking.
Biochemistry 42:11634-11641. [PUBMED]
Hamada K., Shimizu T., Yonemura S., Tsukita Sh., Tsukita Sa., and Hakoshima T.* 2003.
Structural basis of adhesion-molecule recognition by ERM proteins by the crystal structure
of the radixin-ICAM-2 complex.
EMBO J. 22:502-514. [PUBMED]
Kikuchi S., Hata M., Fukumoto K., Yamane Y., Matsui T., Tamura A., Yonemura S., Yamagishi H., Keppler D., Tsukita,Sh., and Tsukita Sa.* 2002.
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile
canalicular membranes.
NatureGenetics 31:320-325. [PUBMED]
Yonemura S., Matsui T., Tsukita Sh., and Tsukita Sa.* 2002.
Rho-dependent and -independent activation mechanisms of Ezrin/Radixin/Moesin proteins:
An essential role of polyphosphoinositides in vivo.
J. Cell Sci. 115:2569-2580 [PUBMED]
Shimizu T., Seto A., Maita N., Hamada K., Tsukita Sh., Tsukita Sa., and Hakoshima T.* 2002.
Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J. Biol. Chem. 277:10332-10336. [PUBMED]
Ishikawa H., Tamura A., Matsui T., Sasaki H., Hakoshima T., Tsukita Sh., and Tsukita Sa.* 2001.
Structural conversion between open and closed forms of radixin: Low-angle shadowing
electron microscopy.
J. Mol. Biol. 310:973-978. [PUBMED]
Hamada K., Shimizu T., Matsui T., Tuskita Sh., Tsukita Sa., and Hakoshima T.* 2001.
Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail
of the adhesion protein ICAM-2.
Acta Crystallogr. D. Biol. Crystallogr. 57:891-892. [PUBMED]
Hamada K., Seto A., Shimizu T., Matsui T.,Takai Y., Tsukita Sh., Tsukita Sa., and Hakoshima T.* 2001.
Crystallization and preliminary crystallographic studies of RhoGDI in complex with the
radixin FERM domain.
Acta Crystallogr. D. Biol. Crystallogr. 57:889-890. [PUBMED]
Nakagawa Y., Yamane Y., Okanoue T., Tsukita Sh., and Tsukita Sa.* 2001.
Outer dense fiber 2 is a widespread centrosome scaffold component preferentially associated with
mother centrioles:Its identification from isolated centrosomes.
Mol. Biol. Cell 12:1687-1697. [PUBMED]
Hamada K., Shimizu T., Matsui T., Tsukita Sh., Tsukita Sa., and Hakoshima T.* 2000.
Structural basis of the membrane-targeting and unmasking mechanism of radixin FERM domain.
EMBO J. 19:4449-4462. [PUBMED]
Hamada K., Matsui T., Tsukita Sh., Tsukita Sa., and Hakoshima T.* 2000.
Crystallographic characterization of the membrane-binding domain of radixin.
Acta Crystallogr. D. Biol. Crystallogr. 56:922-923. [PUBMED]
Xiao S., Komiya K., Tochikura T.S., Sagara J., Tsukita Sa., and Kawai A.* 2000.
The rabies virion-associated 100-kDa polypeptide (VAP100) is a host-derived minor component
of the viral envelope.
Microbiol. Immunol. 44:657-68. [PUBMED]
Tsukita Sa. and Yonemura S.* 1999.
Cortical actin organization: Lessons from ERM (ezrin/radixin/moesin) proteins.
J. Biol. Chem. 2 274:34507-34510. [PUBMED]
Matsui T., Yonemura S., Tsukita Sh., and Tsukita Sa.* 1999.
Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol-4-phosphate
5-kinase and not ROCK kinases.
Curr. Biol. 9:1259-1262. [PUBMED]
Maeda M., Matsui T., Imamura M., Tsukita Sh., and Tsukita Sa.* 1999.
Expression level, subcellular distribution and Rho-GDI binding affinity of merlin in comparison with
ezrin/radixin/moesin proteins.
Oncogene 18:4788-4797. [PUBMED]
Hayashi K., Yonemura S., Matsui T., Tsukita Sa., and Tsukita Sh.* 1999.
Immunofluorescence detection of ezrin/radixin/moesin (ERM) proteins with their carboxyl-terminal
threonine phosphorylated in cultured cells and tissues: Application of a novel fixation protocol
using trichloro-acetic (TCA) as a fixative.
J. Cell Sci. 112:1149-1158. [PUBMED]
Yonemura S., Tsukita Sa., and Tsukita Sh.* 1999.
Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of
microvilli in collaboration with activated ERM proteins
J. Cell Biol. 145:1497-1506. [PUBMED]
Doi Y., Itoh M., Yonemura S., Ishihara S., Takano H., Noda T., Tsukita Sh., and Tsukita Sa.* 1999.
Moesin gene knockout: Normal development of mice and unimpaired cell adhesion /cell
motiltiy/actin-based cytoskeleton without compensatory up-regulation of ezrin and radixin.
J. Biol. Chem. 274:2315-2321. [PUBMED]
Chishti A.H., Kim A.C., Tsukita Sh., Tsukita Sa.* et al. 1998.
The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the
membrane.
TIBS 23:281-282. [PUBMED]